Ryder survived both the Santa Ana wind and the tougher South Course with just one bogey to reach 12-under 132 and take a three-stroke lead over Brendan Steele, who shot a 70 on the South Course. Tano Goya was two more shots back after a 67 on the North Course.
The Santa Ana wind blowing out of the desert and down the mountains raked the course most of the day, with gusts up to 30 mph. It sent leaves, branches and even a tumbleweed onto greens, and cardboard trash cans tumbling down hillsides.
"Yesterday was very easy, today was very hard," said Rahm, who took his first tour win here in 2017 and then won the 2021 U.S. Open on the blufftop municipal course overlooking the Pacific Ocean. "It's never easy out here on either one of the courses, especially the South, and when you get poa annua bumpy greens with this wind, it can be a bit of a nightmare, so glad I made a few."
Rahm, ranked No. 3 in the world and looking to win for the third time three starts this year, rebounded from an opening 73 on the South Course by getting hot on his back nine. He eagled the par-5 fifth and then had three straight birdies. He had another eagle chance on the par-4 seventh but his long putt caught the left edge and skidded about a foot away.
After his frustrating opening round, "anything in the 60s would have been amazing," Rahm said. "What I shot today, man, I'm going to be skipping out of the golf course today because it's a great round of golf."
Rahm, who won The American Express last weekend, started on the back nine and opened with consecutive birdies but bogeyed his third and ninth holes. He was even going into the par-5 fifth, when he started his run with an eagle.
"Holes five through nine, with or without wind is where you can take advantage of the course," the Spanish star said. "Luckily, I've been hitting it really good. There's no difference between those holes or any other five, four holes you can pick throughout the round, it's just kind of guessed with the wind right in all of them. I think maybe I was a little more aggressive after that second shot on 6 and got in the mentality of making birdies instead of being a little tentative, which is easy to do when it's blowing as hard as it was blowing today."
Rahm, who went from tied for 116th on Wednesday to tied for 14th, said the cut line never came to mind.
"I was playing with the mindset of catching up to the leaders as much as possible, that's it."
Ryder, a 33-year-old who has never won on the PGA Tour, opened some distance after sharing the first-round lead with Aaron Rai and Brent Grant. Grant was in a group of six at 6 under.
"Yeah, it feels great. The thing I've been kind of telling myself is to just try and embrace it," Ryder said. "It's not a position that I've been in a lot, you know, so just trying to enjoy it. It's kind of why we play, so just trying to look around and enjoy the moment.
"And I'm just doing everything pretty solid. It starts off the tee for me, I'm driving it well. My iron play is really good, so I feel like if I put it in the fairway, I can attack. And I don't think I really missed many shots today. I missed a couple fairways, but the irons have been really good."
Will Zalatoris, ranked No. 7 in the world, missed the cut after shooting 5-over 77 on the South Course.
The final two rounds will be on the South Course.