Up next is a road game Tuesday at Alabama (13-5, 3-0). The Tide won at Mississippi State on Saturday night.
The Tigers will be big underdogs against Alabama, unranked in polls but a top-10 team in both KenPom and NET rankings.
Alabama boasts the nation's top-ranked offense, according to KenPom, which could mean trouble for a pedestrian Mizzou defense.
Sean East leads Mizzou at 17.1 points per game. Noah Carter (12.8), Tamar Bates (10.8) and Nick Honor (10.3) also average double figures in scoring.
Alabama is led by Mark Sears (20.3 points per game), Aaron Estrada (13.1) and Grant Nelson (12.6).
Mizzou has lost three straight vs. Alabama and is 1-7 all-time vs. the Crimson Tide on the road.
Here's how to watch Mizzou at Alabama basketball:
Game time: 6 p.m. CST/7 p.m. EST Tuesday, January 16
Location: Coleman Coliseum in Tuscaloosa, Alabama
TV channel: SEC Network
Live stream: SEC Network
Radio: KTRS (550 AM and 106.1 FM) in St. Louis, other radio affiliates across Missouri and online through the Varsity Network.
Streaming apps: Varsity Network app on the Apple Store or Google Play (free); TuneIn app on the Apple Store or Google Play. (requires subscription)
Key missed free throws in overtime doomed Mizzou vs. South Carolina.
Nick Honorâs recent offensive woes have presented a headache for the Tigers.
Mizzou commit Aaron Rowe has turned into a spectacle at Father Tolton.
Tuesday's loss at Kentucky felt like a rerun, a big deficit then a comeback.
The SEC's depth is causing a lot of suffering, Jeff Gordon writes.
A pair of long scoring droughts doomed Mizzou in its SEC opener Saturday vs. Georgia.
The Tigers face some big questions in Southeastern Conference play.
Mizzou's Tamar Bates is heating up of late.
League play will bring tough test after tough test for Mizzou, Jeff Gordon writes.
This year's Tigers have more of a defensive focus than last year's squad.